![]() These findings support the assays' utility in clinical diagnosis and research in MENA populations. The ELISA kits demonstrated robust diagnostic performance compared to the IB/WB assays. Suitable for Western Blot and Immunoprecipitation applications. People want to obtain the western blot to get the most accurate. Mouse monoclonal for herpes simplex virus type 1 (HSV-1) capsids protein VP5. CONCLUSION: The assays showed excellent concordance with one another, and with a high kappa statistic. Herpes experts agree that the herpes western blot is by far the best confirmatory antibody test. Positive and negative predictive values were >97% and >83%, respectively. Compared against IB/WB, HerpeSelect ® and Euroimmun had sensitivities and specificities >96% and >86%, respectively. This online-only service will help you obtain. Formerly the Westover Heights Clinic, We are now the Westover Research Group. RESULTS: Across all six comparisons between assays, positive percent agreement ranged between 95.7% (95% CI: 91.4-98.3%) and 100.0% (95% CI: 97.8-100.0%). In addition, people seeking a herpes western blot will be able to obtain that through a research study comparing the traditional screening test to the gold standard herpes western blot. Twenty specimens were randomly selected from 10 MENA nationalities (Egypt, Iran, Jordan, Lebanon, Pakistan, Palestine, Qatar, Sudan, Syria, and Yemen total = 200), and tested for HSV-1 antibodies. STUDY DESIGN: Blood specimens were collected from blood donors in Doha, Qatar, June 2013-2016. OBJECTIVE: To investigate performance of two commercial ELISA kits, HerpeSelect ® 1 ELISA and Euroimmun Anti-HSV-1 (gC1) ELISA (IgG) and two commercial immunoblot (IB)/Western blot (WB) assays, HerpeSelect ® 1 and 2 Immunoblot IgG, and Euroimmun Anti-HSV-1/HSV-2 gG2 Euroline-WB (IgG/IgM) in detecting HSV-1 antibodies in a Middle East and North Africa (MENA) population. However, their performance characteristics could vary among global populations. Performance evaluation of four type-specific commercial assays for detection of herpes simplex virus type 1 antibodies in a Middle East and North Africa population.īACKGROUND: The number of diagnostic assays for the detection of herpes simplex virus type 1 (HSV-1) antibodies has increased over the years.
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